Answer
The two maps depicting the allele frequency of sickled hemoglobin (HbS) alongside malaria endemicity in Africa illustrate a clear correlation. The malaria-free areas are represented by the lighter shades of gray to red on the allele frequency heat map, which indicates that the HbS allele frequencies in these regions fall between 0 and 2.02. Therefore, the correct answer is A) When an area is malaria free, the HbS allele frequency is between 0 and 2.02.
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